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Pharmacology

Department of Pharmacology

The Department of Pharmacology was started in the year 2008. Since then the Department has shown a good progression in the field of teaching the subject MBBS, Allied health Sciences students.

The objective of our department is mainly to provide such scientific data, using which one can choose a drug treatment of proven efficacy and safety from the various options available, to suit the patient.

Today, it is a full-fledged teaching cum services Department with State of the art Museum, Pharmacovigilance, Drug formulations and Pharmacy services.

Vision

  • To promote knowledge of drugs to students and doctors
  • To guide the doctors in treating the patient by choosing the right drug

Mission

  • Optimization and individualization of curriculum, knowledge (both theoretical and practical) to the stakeholders (MBBS STUDENTS, Post-graduate students, and Allied Health Students and B.Sc Nursing students)
  • Dishing out scientific and rationalistic pharmacology to students and practicing physicians and related health care professionals.

PROFESSOR & HOD

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Dr. Venkatadri.N MBBS M.D
PROFILE SUMMARY

Dr. Venkatadri.N, Professor & HOD of Pathology and Second Year MBBS Coordinator at SSSMCRI. He loves teaching Undergraduates

Detailed CV Attached


Professor

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Dr.Shree Lakshmi Devi.S MBBS, MD Pharmacology
PROFILE SUMMARY

I am Dr.Shree Lakshmi Devi.S currently working as a professor in Pharmacology with teaching experience of more than eight years and has been teaching undergraduate medical students and allied health science students at SSSMCRI. I have been trained in clinical pharmacology, Experimental Pharmacology, Pharmacotherpeutics, Toxicology, Pharmacovigilance, Geriatric pharmacology, Good clinical practice, Bioethics, Statistics and Clinical trial monitoring. At SSSMCRI I am member secretary of PVC, Joint Secretary of WEF, member of MEU and IRC.

Detailed CV Attached

Associate Professor

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Dr. Lavakumar S MBBS and BDS
PROFILE SUMMARY

Dr. Lavakumar S, Associate Professor in the Department of Pharmacology at Shri Sathya Sai Medical College and Research Institute, Ammapettai, Kancheepuram District. Seek to be an active part of a reputed organization, there by contribute in growth and development of organization and to develop myself efficiently and have a growth in professional and capacity building career. Key areas of interests are: Clinical Pharmacology and Therapeutics, Medical Education

Detailed CV Attached

Assistant Professor

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Dr. SoundaryaPriyadharsini. K MBBS, MD inPharmacology
PROFILE SUMMARY

Dr. SoundaryaPriyadharsini.K, Assistant Professor of Pathology and 3 Year MBBS Coordinator at SSSMCRI. He loves teaching Undergraduates

Detailed CV Attached

Assistant Professor

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DR. Sravanthi Lakshmi.M MBBS, MD inPharmacology
PROFILE SUMMARY

Dr. Sravanthi Lakshmi.M, Assistant Professor of Pathology and 3 Year MBBS Coordinator at SSSMCRI. He loves teaching Undergraduates

Detailed CV Attached

Associate Professor

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DR. Maduram.A M.D ( Pharmacology)
PROFILE SUMMARY

DR. Maduram.A, Assistant Professor of Pathology and 3 Year MBBS Coordinator at SSSMCRI. He loves teaching Undergraduates

Detailed CV Attached

Assistant Professor

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DR. Mali KalpanaRamanna MBBS, MD inPharmacology
PROFILE SUMMARY

DR. Mali KalpanaRamanna, Assistant Professor of Pathology and 3 Year MBBS Coordinator at SSSMCRI. He loves teaching Undergraduates

Detailed CV Attached

Facilities

CENTRAL ANIMAL HOUSE

Central Animal House (CAH) at SSSMCRI under Pharmacology was established in 2008 to accomplish the requirements of various investigators from different departments in SSSMCRI. It is located in a secluded corner of the campus, away from noise and pollution, providing an excellent environment for animals. The facility is equipped for small animal experimentation with quarantine and experimental rooms for rodents and rabbits. The Animal House is conventional type of animal house where each species can be housed in individual rooms, in which the temperature, humidity, dark and light cycles are monitored. To monitor the health status of the animals we have a Veterinary Doctor. CAH is registered with the committee for the purpose of control and supervision of experiments on animals (CPCSEA), Ministry of Environment and Forests, Government of India, New Delhi (Registration Number: 1342/AC/10/CPCSEA activities happening in laboratory animal research at Central Animal House at SSSMCRI are performed as per the guidelines of CPCSEA, New Delhi as well as institutional guidelines under the supervision of Institutional Animal Ethics Committee (IAEC).

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RESEARCH LABORATORY

It’s well equipped with research instruments to perform various researches in the field of

  • Neuropharmacology
  • Cardio-pharmacology
  • Analgesic drugs

S.No

Name of Research instruments

1

Actophotometer – 1

2

Pole Climbing Response Apparatus – 1

3

Tablet Disintegration Machine – 1

4

Stimulator General Purpose(Arthur Thomas) – 1

5

Filter photo calorimeter – 1

6

Magnetic Stirrer – 1

7

Telethermometer Digital 6 Probes – 1

8

Rota rod 3 Compartments – 1

9

Two unit Thermostatic Organ Bath – 1

10

Digital Physiograph – 10

11

Hotplate – 1

12

Laboratory pH Meter – 1

13

Electro   Convulsiometer – 1

14

Digital Analgesiometer – 1

15

Super  Speed Kymograph Assembly – 1

16

Incubator – 2

17

Standard Mercury Manometer – 2

18

Gaddum’s Outflow Recorder – 1

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MUSEUM

Department of pharmacology has a well-established museum with a seating capacity for 50students. It has a comprehensive collection of charts and posters for Undergraduates and Postgraduates students, to further enhance the interest in the history of Pharmacology and promote its further development for the benefit of the general public. There are charts depicting Clinical Pharmacology, Mechanism of drug action, Drug interaction and Pharmacognosy. It is updated regularly to keep in touch with dynamic developments in the field of Pharmacology

A separate section for crude drugs, medical devices and drug specimen are available.

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I.PHARMACOVIGILANCE

Unit of Pharmacovigilance is actively reporting ADR to zonal center. ADR monitoring at SSSMCRI involves serious adverse events, customer ADR reporting and reporting blood and blood products related reaction (Haemovigilance).

Pharmacovigilance committee constitutes 14 members from various clinical departments and every second Thursday the committee meeting is conducted to review the Adverse drug reactions and PVC activities at SSSMCRI.

PVC members clinical rounds at 10.30 to 11.00

As the staff nurse will be the first person to be in contact with patients ,PVC has conducted sensitization program for staff nurses and Pharmacist about Pharmacovigilance and ADR form filling. Every year special PV program are conducted to sensitize the post graduate students about ADR monitoring and filling ADR forms.

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II.Haemovigilance

A centralized hemovigilance program was launched in the country on December 10, 2012, to assure patient safety and promote public health through a well-structured program for monitoring of adverse reactions associated with blood and blood product transfusions.

Pharmacology with Department of Pathology has initiated haemovigilance program in SSSMCRI. We are collecting and reporting Senstization program on Haemovigilance it covered all Pathologist and blood bank officer.

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COURSES OFFERED

  • MD Pharmacology
  • PhD Pharmacology
  • MBBS
  • B.Sc Allied Health Sciences
  • B.Sc Nursing
MD Pharmacology

The department of Pharmacology has a 3 year PG training program in experimental and clinical pharmacology and research with inbuilt formative assessment and provision of constructive feedback to the students. The postgraduate educational activities include postgraduate seminars, journal clubs and putting relevant articles on sounding board. In addition during second year they are posted in various clinical departments. PG students have enormous scope for involvement in research activities in the form of thesis work as well as other experimental and clinical studies.

PhD Pharmacology

The department also provides a four year PhD program in Pharmacology with scope of research in the field of Neuropharmacology and pain, Cardiovascular drugs, Drug safety, animal experiments and clinical Pharmacology.

MBBS

Department of Pharmacology runs theory and practical programs for undergraduate students. The theory comprises of large group interactive lectures, symposia and small group teaching in the form of tutorials. Practical’s are conducted in the form of demonstrations, simulated videos and case studies.

In this era of competition, medical students constantly need to keep themselves updated with medical knowledge as well as with the happenings around them. There is need to nurture self-learning skills in students, so that they become lifelong learners. There is growing evidence that those who take initiative in learning learn more deeply & permanently than those who don’t. Keeping this in mind, the department has initiated following activities: Seminars, Problem solving Exercises, Prescription writing and exercises in concept of essential drugs.

B.Sc Allied Health Sciences and B.Sc Nursing

We offer Pharmacology training for B.Sc Anaethesia Technology, B.Sc Physician Assistance and B.Sc Optometry students. In addition to which training in clinical Pharmacology is given to II year B.Sc nursing students.

LIST OF PUBLICATIONS

I. DR. N. VENKATADRI

  1. Ramaswamy S, Venkatadri N, Bapna JS..An investigation into the possible development of chronic tolerance to analgesia and dependence on prolactin.Fundamental and Clinical pharmacology,1(1987)445 to 449
  2. Curriculum for interns of Essentials Drugs and Cost effective prescribing. The Indian Journal of Medical Education. 1987: 26(2); May to August
  3. G. Lenin Kamatchi Dinesh Chandra M. Rajasekaran K. Madhusudana Rao N. Venkatadri J. S. BapnaAntagonism of Diazepam Hyperphagia by propranolol in Rates.Drugs Development and Research 13:231-236,1998
  4. K. R Sethuraman, C Adithan, C. H Shashindran, N Venkatadri, A Venkatraman, D. G Shewade, S Chandrasekar, J. S BapnaA comparative clinical trial –Aerosol Budesonide and Oral prednisolone in patients of Bronchial Asthma.Lung India (1990)VIII No.1 P(11-14)
  5. Madhusudanarao K1, Bapna JS, Adithan C, Ray K, Venkatadri N, Kamatchi GL, Seetharaman ML, Bahadur P.Effect of short course Chemotherapy on Salivary paracetamol Elimination. Clinical and Experimental pharmacology and physiology (1998)15,639-643.
  6. Madhusudanarao K1, Bapna JS, Adithan C, Ray K, Venkatadri N, Kamatchi GL, Seetharaman ML, Bahadur PEffect of pulmonary Tuberculosis on Salivary paracetamol Elimination.Journal of Medical Science Research, 1998, 16,481
  7. S.S.raju h.N.gopalakrishna,N.venkatadri Effect of propranolol and nifedipine on maximal electroshock-induced seizures in mice: individually and in combination Pharmacological Research Volume 38, Issue 6, December 1998, Pages 449-452
  8. S.Ramaswamy, N. Venkatadri. An investigation into the possible development of chronic tolerance to analgesia and dependence on prolactin. Journal Of Fundamental And Clinical Pharmacology.1987; Volume1, Issue6
  9. Indian Medicinal plants –An Allopathic perspective(proceedings of National Symposium on medical plants of India, St.Joseph’s College publications Trichy.feb.2001)

II. Dr. A. MADURM

  1. Maduram A, Harikrishnan R. Prescription pattern of Anti Hypertensive drugs in Shri Sathya Sai Medical College & Research Institute.International Journal of Basic Medical Science - June 2013, Vol : 4, Issue : 2
  2. Dr. Maduram;Prescribing Practices of Psychiatrists in treatment of Depression. National journal of Basic medical sciences;Vol5, Issue 3 Jan-March 2015 and page: 97-101.
  3. Kamaraj R, Maduram A, Raaman N. Hepatoprotective Activity of Various Extracts of Clausena Dentata (Willd.) Roem. (Syn. Clausena Willdenovii Wight. And Arn.) Rutaceae. Asian Journal of Pharmaceutical and Clinical research.2017; 10(10): 310-13
  4. Kamaraj R, Maduram A. Analgesic and Anti inflammatory Activity of Various Extracts of Clausena Dentata (Willd.) Roem. Asian Journal of Pharmaceutical and Clinical research.2018; 11(2): 413-16
  5. Mohana Rupa, Maduram A, Jagan Nadipelly.Efficacy of ciclesonide, budesonide and beclomethasone dipropionate in moderate persistent bronchial asthma: a comparative study. International Journal of Basic & Clinical Pharmacology. October 2019:8(10);1-4

III.Dr.SHREE LAKSHMI DEVI.S

  1. Shreelakshmidevi. S, Abilash S. C, Basalingappa S. The Rationale of Caffeine Consumption and its Symptoms During preparatory and Non-Preparatory Days: A Study Among Medical Students.BiomedPharmacol J. 2018;11(2):1153-1159.(Scopus indexed)
  2. Shree Lakshmi Devi S., Basalingappa S., Abilash S. C.:A study of adverse drug reactions among elderly patients in a tertiary care hospital.International Journal of Basic &Clinical Pharmacology; 2017 :6 (8) :1-6.
  3. Shree Lakshmi Devi S, Abilash SC, Sengottuvelu S. Evaluation of antiulcer and antioxidant potential of Ipomoea Reniformis leaf extract against experimentally induced ulcer in rats. Int J Basic ClinPharmacol 2017;6:1602-7.
  4. Shreelakshmidevi. S, Abilash SC, Premlal KR , Balamuruganvelu S , Geethavani B3 , Vedapriya DR , Jaikumars Antispasmodic activity of aqueous leaf extract of xanthium strumarium on isolated rabbit jejunum - International Journal of Innovative Drug Discovery. 2014;4(3):1-3
  5. Shreelakshmidevi. S, Abilash SC, Premlal KR , Balamuruganvelu S , Geethavani B , Jaikumar S. Antidiarrhoeal activity of aqueous leaf extract of xanthium strumarium on castor oil induced diarrhea in rats. Inter. J. Of phytotherapy2015; 5(1):1-3.
  6. Chandrakumari A, Lingappa H, Shreelakshmidevi. S. Evaluation of Diagnostic Efficacy of Pipelle Endometrial Sampling in Abnormal Uterine Bleeding. Journal of Clinical and Diagnostic Research. 2018;12(5):1-4.
  7. Abilash SC, Shreelakshmidevi. S. Histopathological interpretation of colonic mucosal biopsies with clinical correlation: a study in a tertiary care hospital kerala. Annals of Pathology and Laboratory Medicine, September-October 2017;4(5):567-72.
  8. Abilash SC, Shreelakshmidevi. S, B Krishnaswamy, Balamuruganvelu s hematological survey among school children in rural community of chidambaram, cuddalore a district in tamilnadu, India European Journal of Molecular Biology and Biochemistry. 2016;3(1):48-51.
  9. Balamuruganvelu S, Abilash SC, Shreelakshmidevi. S,et al. Antioxidant activity of limoniaacidissimain high fat diet induced hyperlipidemic rats. International Journal of Phytopharmacology.2015;6(4):181-183
  10. Abilash SC, Hemalatha A L, Shreelakshmidevi. S. “Diagnostic Efficacy of Bronchial Brush And Bronchoalveolar Lavage Cytology in Bronchopulmonary Lesions. : Indian Journal of Pathology: Research and Practice / Volume 6 Number 3 / July - September 2017 (Part-II); 701-707.
  11. Anebaracy V, Geethavani B, Balamuruganvelu S,ShreeLakshmidevi S et al. Anithyperlipidemic activity of ethanolic extract of limoniaacidissima roots in high fat diet induced hyperlipidemic rats. International Journal of Phytotherapy.2015;5(2):94-97.
  12. Anebaracy V, Geethavani B, Balamuruganvelu S, Sangamithra V, ShreeLakshmidevi S, Jaikumar S: Antimicrobial activity of ethanolic root extract of limoniaacidissima. Journal of Science.2015;5(7) :476-478.
  13. Abilash SC, HasafKolakkadan, Gitanjali MM, Shreelakshmidevi S et al. Histopathologic spectrum of upper gastrointestinal tract mucosal biopsies: a retrospective study. Scholars Journal of Applied MedicalSciences. 2016; 4(5E):1807-1813.

IV. Dr. Lavakumar S

  1. Lavakumar S, Lahon K, Pandian J.Effect of sub-acute administration of celecoxib on antidepressant effect of fluoxetine in albino mice.International Journal of Pharma and Bio Sciences 2013 Jan; 4(1)
  2. Pandiamunian J, Lavakumar S, Pandian J, Somasundaram G.Evaluation of anxiolytic effect of pet ether extract of Portulaca oleracea in mice;International Journal of Applied Biology and Pharmaceutical technology 2012 Oct; 3(4)
  3. Pandiamunian J, Lavakumar S, Pandian J, Somasundaram G.Evaluation of anxiolytic effect of pet ether extract of Portulaca oleracea in mice;International Journal of Applied Biology and Pharmaceutical technology 2012 Oct; 3(4)
  4. Lahon K, Pandian J, Lavakumar S. Effect of sub-acute administration of propranolol on antidepressant effect of alprazolam in albino mice. Asian J Phar Biol Res. 2012; 2(4): 240-244
  5. Prabal Joshi, Lavakumar Somu, Somasundaram G, Jaiganesh K. A survey and feedback analysis on undergraduate medical students teaching methods; American Journal of Advances in Nursing Research. 2014;1(3)
  6. Prabal Joshi, Lavakumar Somu, Somasundaram G A study on neonatal intensive care unit prescription pattern of antibiotics utilization in a tertiary care centre. International Journal of Advances In Case Reports;2014;1(2)
  7. Lavakumar S , Manimekalai K, Karthikeyan K.Outcome assessment of intravenous immunoglobulin therapy as an adjuvant in treatment of neonatal sepsis, a prospective observational study; Int J Pharm Bio Sci 2015 Oct; 6(4): 963 – 70
  8. Jacob Jesurun RS, Lavakumar S. Nephroprotective effect of ethanolic extract of Abutilon indicum root in Gentamicin induced acute renal failure in wistar albino rats. Int J Basic Clin Pharmacol.2016; 5(3): 841-45.
  9. Lavakumar Somu, Jacobjesurun; A study on the level of drug compliance among the outpatients who are on a long term drug therapy in a tertiary care teaching hospital at Kancheepuram District in tamilnadu. Asian Journal of pharmaceutical and clinical research;Vol 10 (3),March 2017
  10. Lavakumar Somu, Arivazhagan. Drug Utilisation Pattern of Antibiotics In An Intensive Care Unit In A Tertiarycare Teaching Hospital In Kancheepuram District. Int Journal of Current research: 2017;9(5):51440-2
  11. Jesurun RS, Lavakumar S. Pattern of Medical emergencies and prescription pattern of drugs in an emergency medicine department in a tertiary care teaching hospital in Kancheepuram district; Mintage Journal of Pharmaceutical and Medical Sciences: 2018;7(2)
  12. Lavakumar S. A study on adverse effects of antidepressants in a tertiary care teaching hospital. Indian J Pharm Biol.Res. Dec 2018:6(4):32-34
  13. Lavakumar S, Jacob Jesurun RS. A prospective open labeled study of effect of Vildagliptin with Metformin in patients with Type 2 Diabetes Mellitus. Int J Basic Clin Pharmacol. 2019 Aug;8(8):1880-83

V. Dr. SoundaryaPriyadharsini. K

  1. SoundaryaPriyadharsini K, Nirmala P, Ashok Kumar P, Krishna Prasad T;Effect of Lutein in the expression of PPAR? and LDLR in hypercholesterolemic male Wistar Rats; International Journal of Basic & Clinical Pharmacology April 2018;Vol 7; Issue 4
  2. SoundaryaPriyadharsini K, Nirmala P, Ashok Kumar P;Effect Of Lutein In Hypercholesterolemia Induced Oxidative Stress In Male Wistar Rats;Int J Curr Pharm Res, Vol 7, Issue 2, 97-100

VI. Dr. Mali KalpanaRamanna

  1. Mali KalpanaRamanna, Ruckmani A., Siddharam S. Janti, MadhaviEerike, R. LakshmipathyPrabu.Burden of therapy in patients suffering from diabetes & hypertension.International Journal of Pharmacy and Pharmaceutical Sciences. 2017 Vol 9, Issue 5

VII. Dr.Lakshmi Sravanthi Mukku

  1. Sravanthi.M, Jagadeesh A, Ramya Rachamanti. Medical student’s perception of teaching-learning of pharmacology in a medical college. International Journal of Basic and Clinical Pharmacology.2018; 7(4):665-668.
  2. RR, VPK, MCD, Sravanthi,M- Antimicrobial utilization in wound infections in a tertiary care hospital. Biomedical & Pharmacology journal.2018; Vol. 11(1), 159-165. (Scopus indexed)

List of ongoing projects:

  • Study on the effects of Sevoflurane and Isoflurane on post operative revovery criteria in Adult patients – Dr. Soundarya

Extra mural funded project (Ongoing):

  • A study to assess the drug adherence among TB patients using Short Tubercular Drug adherence rating scale – Dr. Shree Lakshmidevi.Funding agency: TB Association of India

List of completed projects:

    1. A study on evaluation on the level of drug compliance among the outpatients who are on a long term drug therapy in a tertiary care teaching hospital – a questionnaire based prospective study- Dr. Lavakumar
    2. Drug utilization pattern of antibiotics in an ICU in a tertiary care teaching hospital-Dr. Lavakumar
    3. Pattern of medical emergencies and prescription pattern of drugs in an accident and emergency care unit in a tertiary care teaching hospital - Dr. Lavakumar S
    4. A study on adverse effects of antidepressants in a tertiary care teaching hospital. - Dr. Lavakumar S
    5. A Comparative Study of Didactic lecture and Case Based learning in II year Pharmacology Curriculum- Dr. Lavakumar S
    6. A Study on commonly prescribed antimicrobial agents and resistance pattern in tertiary care hospital – Dr. Shree Lakshmidevi

STS ICMR PROJECTS:

S. No

Research Title

Year

Student name

Faculty Guide

Funding Agency

1

Prescription pattern of  Anti Hypertensive drugs in Shri Sathya  Sai Medical College & Research Institute

2012

Mr. Harikrishnan

Dr. Maduram A

ICMR

2

Effect of clofazamine on carrageenan  induced acute arthritis in albino wistar rats

2017

 

Mr. Balaji

 

Dr. Shree Lakshmidevi

ICMR

3

Evaluation of analgesic activity of manilkara zapota fruit skin in experimental animal model

2017

 

Ms. Sushma

 

Dr. Kalpana

ICMR

4

Distribution pattern of adverse effects of Bronchodilators and its causality assessment in a tertiary care teaching hospital

2019

Ms. Keerthana

Dr. Lavakumar

ICMR